The inability of a couple to conceive within a year despite unprotected regular sexual intercourse is called infertility. Approximately 10-15% of couples face infertility as a problem.
In cases where the mother is younger than 35 years old, it is necessary to consult a doctor for 1 year, and in cases where the mother is older than 35 years, if pregnancy has not occurred despite having unprotected regular sexual intercourse for 6 months.
In unexplained and usually male-induced infertility, insemination treatment can be tried before IVF. Insemination therapy is not recommended if there is a decrease in the woman’s egg cells and she has waited too long for pregnancy, or if there is a problem with the woman’s tubes. In insemination treatment, the egg is cracked by stimulating the ovary of the mother-to-be. The sperm of the father-to-be is washed and the best ones are selected and transferred to the uterus.
Humans normally have 46 chromosomes. Two of these are the X and Y chromosomes, which are sex chromosomes. Women have two X chromosomes (46XX), while males have one X and one Y chromosome (46XY). Disorders in the sex chromosomes are the cause of infertility. In men, the loss of genetic material in some parts of the Y chromosome leads to azoospermia or severe sperm count and shape-movement disorder, leading to infertility. Likewise, the loss of X chromosomes in women causes the ovaries to fail to function and therefore causes infertility. Genetic defects in autosomal chromosomes other than sex chromosomes also lead to recurrent miscarriages, infertility and genetic disorders in the fetus in couples.
In cases of hypogonadotropic hypogonadism, which is called primary amenorrhea and in which the hormone cycle that stimulates the ovaries does not work, women can not menstruate at all. Ovulation is achieved by reinforcing these missing hormones and pregnancy is achieved by directing the couple to the appropriate assisted reproductive technique. In other cases that cannot menstruate, the genetic syndrome known as Turner syndrome (45, X0), premature ovarian failure leading to early menopause, and it is not possible to achieve pregnancy with their own eggs in menopausal women. These cases can become pregnant with egg donation method.
Research shows that 40% of infertility cases are due to female factors, 40% to male factors, and 20% to unknown causes.
Obesity is defined as a body mass index (BMI) greater than 30 kg / m2, and overweight as a BMI of 25-30 kg / m2. (Calculate your body mass index here.) Obesity is linked to many medical problems, including infertility. Infertility in obese and overweight women is primarily due to ovulatory dysfunction.
IVF centers determine their success by pregnancy rate and live birth rate. The success rates of the centers increase with the correct implementation of all steps of IVF treatments. A couple receives well-practiced ovulation induction, egg collected at the right time, correct microinjection with well-selected sperm, and finally transfer of the embryo with a good technique will provide a high pregnancy rate. In the selection of an IVF center, it is necessary to pay attention to the experience of the center, the technical equipment in the laboratory and healthy pregnancy rates.
Egg collection is performed under anesthesia. In the process that takes about 5-10 minutes, the follicle fluids in your ovaries are collected with the help of ultrasound and the eggs in this follicle are extracted by embryologists under a microscope.
The transfer process is a painless procedure and anesthesia is not applied. After the transfer, detailed information is given about the situations to be considered and the medication to be used.
As a result of scientific studies, there was no increased risk of congenital anomalies or genetic diseases in fetuses compared to fresh embryo pregnancies in pregnancies obtained by frozen embryo transfer. Today, embryo freezing is a standard pillar of IVF treatments and is used as a method that increases the chance of pregnancy.
No, the pregnancy rate does not decrease.
Freeze storage of ovarian tissue is a method that can be performed for women who are undergoing cancer treatment or whose fertility is threatened due to early menopause. The ovarian tissue taken by laparoscopic surgery before chemotherapy or radiotherapy is frozen and stored and placed back into the body to regain reproductive functions after cancer treatment. Today, although successful pregnancies and births have been achieved after transplantation, it is still accepted as an experimental treatment method. It is recommended for women who are scheduled for chemotherapy or radiotherapy to treat cancer, who are preparing for bone marrow or stem cell transplants, and who are scheduled for high-dose chemotherapy due to immune system diseases.
Chemotherapy is a treatment method that works with the principle of destroying rapidly dividing cells. The target cell is the cancer cell, but it also destroys the sperm and egg cells, which are hair-hair bulb, gastrointestinal and reproductive cells that divide rapidly in the body. In the same way, radiation therapies damage the sperm and the germ cells that make up the sperm cell. Depending on the type, number and total dose of chemotherapy and radiotherapy, it can lead to irreversible azoospermia in men, that is, the inability to form any sperm, and therefore infertility. Freezing sperm before cancer treatments is the only proven treatment for fertility preservation.
Fallopian tubes are the structures that provide the connection between the uterus and the ovaries. Infections in the tubes can cause obstruction and cause female infertility. The agents that involve the tubes and most often lead to infection are streptococcus, staphylococcal and microplasma bacteria, as well as sexually transmitted chlamydia and gonococcal infections. Tuberculosis infection can also rarely lead to obstruction by involving the tubes. Infections can settle in the tubes with conditions such as intrauterine device application, sexual intercourse, miscarriage, curettage and postpartum, sexual transmission and appendicitis. Blockages in the tubes can interfere with pregnancy in the normal way.
The possibility of daily injections can be very high. Medication that once had to be injected intramuscularly have been replaced by medication that are given a small injection (subcutaneously) under the skin. Such injections are most often taken over a period of 10-12 days, followed by an intramuscular injection of a hormone hCG, which triggers ovulation at the end of the stimulation cycle. Previously available only in intramuscular form, hCG injection is now also available in subcutaneous form (Ovidrel) for patients who wish to avoid intramuscular injection. Although the recombinant subcutaneous form of hCG in ovidrel is not last as long as intramuscular hCG, all indicators are equally effective.
After the egg is removed, patients are prescribed a progesterone hormone supplement to prepare the lining of the uterus for embryo transfer. For most patients, progesterone can be taken in the form of a vaginal tablet or vaginal suppository instead of an injection. In this way, the injection can be completely avoided in the second half of the IVF cycle. Progesterone vaginal tablets and suppositories have proven to be as effective as progesterone injections.
Studies to date show that medication taken in infertility treatments do not increase the likelihood of cancer in women. There is no increased risk for breast and uterine cancers. With all this information, it is important that women who have received hormone therapy have regular routine check-ups.
You can have your preliminary tests done in your own city and share the results with our IVF doctor. Thus, it is determined whether you have any obstacles for the IVF program or pregnancy before the treatment. In this period, prenatal vitamin use should be started. IVF treatments begin on the 2nd day of the woman’s menstrual bleeding and continue for approximately 15-18 days. During this period, you will be checked 6-7 times in our center. Our patients who have menstrual irregularities can use menstrual regulating medication in line with the preference of their doctors. As required by legal procedures, bring the necessary official documents and all medical records with you.
In vitro fertilization treatment is a process consisting of egg development, egg collection, embryo development and embryo transfer. Treatment is started on the 2nd day of the woman’s menstruation. During the development of the egg, the patient is examined by blood tests and ultrasonography, often every other day and sometimes daily. This process takes an average of 9-12 days. At the end of this period, when the eggs reach a certain maturity, a cracking injection is given and egg collection is performed after 2 days. On the day the egg is collected, sperm is taken from the father-to-be and fertilization process is performed. Developing embryos are evaluated according to their quality and number and transferred after 2-6 days.
Patients will have several options regarding the disposal of the remaining embryos. One option is to freeze the embryos for your later use.
Couples who have become pregnant with IVF treatment, especially those diagnosed with unexplained infertility, PCOS, mild male factor and low ovarian reserve, can become pregnant naturally in later periods. Natural pregnancy is not expected in couples treated for tubal factor and severe male infertility.
Our center provides services within the scope of SSI. Patient candidates who intend to start IVF treatment can benefit from state support by receiving an SSI committee report.
Yes, there is an age limit to benefit from SSI support. The woman must be over 23 years of age and not older than 41 years.
Original of IVF committee report, certificate of identity register copy, SSI premium payroll, identity card copy of spouses, photocopy of marriage certificate.
Costs in IVF treatment vary according to each patient. There are many reasons why the prices are different in each center and different for each patient. Many factors such as the causes of infertility, the success rates of the center, the age of the mother-to-be, the drugs used and the IVF treatment methods used lead to the change in prices.
You can call us for detailed information about IVF Treatment and its fee.